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Emergence and spread of Plasmodium falciparum PX1 polymorphisms associated with decreased susceptibility to antimalarials in Uganda

Published by Nature.com By Karamoko Niaré, Bersabeh Tafesse, Mayland Treat, Jacob M. Sadler, Martin Okitwi, Stephen Orena, Victor Asua, Oriana Kreutzfeld, Jenny Legac, Jacob Marglous, Samuel L. Nsobya, Adoke Yeka, Dave Richard, Michael T. Ferdig, Angana Mukherjee, Philip J. Rosenthal, Jonathan J. Juliano, Jeffrey A. Bailey, Melissa D. Conrad · 17 August 2026 at 03:00
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Emergence and spread of Plasmodium falciparum PX1 polymorphisms associated with decreased susceptibility to antimalarials in Uganda
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What the report says

Whole-genome sequencing of clinical isolates of Plasmodium falciparum in Uganda reveals rapid selection of a PX1-associated haplotype linked to reduced susceptibility to commonly used antimalarials.

Read the full report at Nature.com →

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