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Dysregulated cholesterol trafficking through ABCA1 drives neurodegeneration in Parkinson’s disease - Nature

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Dysregulated cholesterol trafficking through ABCA1 drives neurodegeneration in Parkinson’s disease - Nature
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What the report says

This study identifies ABCA1 as a driver of dysregulated cholesterol trafficking in Parkinson’s disease, showing that reducing ABCA1 in astrocytes and neurons decreases cholesterol accumulation, α-synuclein pathology and neurodegeneration in mice.

Read the full report at Nature.com →

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